Surgical Repair Using Biologic Tissue Matrix To Facilitate Tissue Healing: A Case-Based Report

Introduction Surgeons have many prosthetic mesh options available for the reinforcement and repair of soft tissue. For ventral hernia repair, a common type of abdominal wall surgery, the addition of prosthetic mesh has significantly reduced recurrence rates.1 despite some favorable performance characteristics, synthetic mesh has been associated with complications, particularly in complex repairs.2,3 Biologic grafts have a clinical rationale: each type is designed to serve as an extracellular matrix (ecm) scaffolding for neovascularization and eventual remodeling of tissue to resemble the native type.4 however, clinical outcomes may be greatly affected by unique characteristics and manufacturing processes that differentiate the available biologic grafts.5 Xcm Biologic tissue matrix—a sterile, non-crosslinked 3-dimensional matrix derived from porcine dermis—offers preservation of natural fibrous architecture that provides a scaffold for cell ingrowth and proliferation. a proprietary manufacturing process removes cells and dna for host acceptance, minimizing damage to native tissue architecture.6 Xcm has characteristics that make it advantageous for trauma surgery: it’s available in multiple sizes—2 cm × 4 cm to 20 cm × 30 cm—and comes hydrated and immediately ready for use, which eliminates the risk for contamination during soaking.6